The Eosinophil

The Eosinophil

The literature on the eosinophil is vast. In the preface to this book the authors refer to a review published in 1914 which cited almost 3,000 references. That this and much subsequent work has contributed so little to our u.nderstanding of the eosinophil is largely due to the fact that techniques available to study haematogenous cells were inappropriate to the fundamental problems of their ori...

Eosinophil Granuloma of the Skin*

When Martinotti published a study on the histiogenesis of eosinophil cells in the skin in 1923, he first described a previously unknown condition, now known as eosinophul granuloma. Since then, not more than nine cases have been described in the international literature. In all these reports it is interesting to note that the various observers arrived at the diagnosis by the study of the unusua...

Eosinophil Lung

Eosinophil cationic protein is not only a distinctive eosinophil protein

We read with interest the article by Qiu et al (Thorax 2007;62:475–82). In this paper, neutrophils and eosinophils were identified using mouse anti-human neutrophil elastase and anti-eosinophil cationic protein (ECP), both monoclonal antibodies (mAbs). mAbs against ECP have been used to detect total eosinophils, but immunostaining techniques evidenced that the number of ECP cells was higher tha...

Eosinophil cationic protein is not only a distinctive eosinophil protein

We read with interest the article by Qiu et al (Thorax 2007;62:475–82). In this paper, neutrophils and eosinophils were identified using mouse anti-human neutrophil elastase and anti-eosinophil cationic protein (ECP), both monoclonal antibodies (mAbs). mAbs against ECP have been used to detect total eosinophils, but immunostaining techniques evidenced that the number of ECP cells was higher tha...